Is CBD Addictive : More and more studies are revealing the health benefits of CBD. CBD is anti-inflammatory as well as seizure-suppressing, and it can be used to reduce anxiety and relieve stress.
Recently, the popularity of CBD has exploded, spreading around the world and beginning a global cannabis revolution. Hemp-derived CBD is legal in all 50 states as long as the THC content doesn’t exceed 0.3%.
Even in doses as high as 1,500mg daily, CBD is safe and well-tolerated by the WHO.
But is CBD addictive?
Is CBD oil addictive despite the plethora of benefits it offers?
This article will provide you with a complete answer to those questions. We’ll discuss the mechanism of addiction, how CBD affects the nervous system, and how CBD could help people transition out of addiction.
How Addiction Works
Science explains addiction as a complex physiological and psychological response to external stimuli. Addiction is linked to changes in brain structure and function. Psychologists and addiction experts agree that three states can start the addictive process.
We discuss them briefly below
Dopamine gets flooded into the brain when it’s exposed to substances, such as nicotine, caffeine, or cocaine. It builds up in the nucleus accumbens, a part of the brain that plays a key role in addiction.
Addiction depends upon several variables: the speed, reliability, and intensity of the dopamine build-up. The way a substance is given, whether it is smoked, taken internally or intravenously, can affect the dopamine response.
Various experts say that pleasure-seeking may not be the only factor involved in addiction. In fact, the information that led to it may even be more important. Dopamine may form and strengthen the feelings of pleasure, but it is the very activity that led up to them.
Almost all theories regarding addiction cite reward-related learning as the main source of addiction. Dopamine works together with glutamate as another major neurotransmitter to lead the brain to associate pleasurable feelings with the behavior that leads to them.
Prolonged Exposure to Certain Substances
Prolonged Exposure to Certain Substances It is believed that the continuous use of certain substances can cause neural cells located in the prefrontal cortex and nucleus accumbens to become dependent upon activation from these active compounds. Users then seek out the addictive substance more often, resulting in a less intense psychoactive experience.
Some substances cause you to build tolerance. This is particularly dangerous with drugs like opioids, where the overdose risk is very high.
A user who attempts to quit cold turkey can experience severe withdrawal symptoms. Withdrawals can include headaches, tremors, pain in the bones and muscles, nausea, vomiting, and irritability.
What is CBD and How Does It Work?
CBD is one of two major components in cannabis. Unlike its counterpart, THC, CBD lacks psychoactive properties, meaning it won’t make you high. It may balance out THC’s psychoactivity by modulating its action in the brain.
A major receptor in the endocannabinoid system, the central regulatory system of all animals, sends messages throughout the body, delivering signals for the brain to interpret. The brain then regulates important processes throughout the body, helping it maintain restorative homeostasis.
Scientists believe that CBD might support homeostasis through multiple biochemical pathways. Researchers think that CBD may interact with the endocannabinoid system, which is sensitive to a neurotransmitter named serotonin.
Serotonin is a major player in mood regulation; it can also intensify feelings of happiness and relaxation. CBD acts as a natural inhibitor of the 5-HT1A receptors. It blocks its reuptake in the brain, allowing higher concentrations of the neurotransmitter to circulate in the body.
CBD may also affect the nuclear receptor PPAR-gamma, which affects glucose metabolism and fat storage. CBD may use a similar mechanism to interact with the TRPV1 receptors by tapping them and blocking pain perception.
Let’s take a look at those interactions in terms of managing addiction and withdrawal symptoms, but first let’s look at the title question.
CBD and Addiction: Is CBD Oil Addictive?
Since CBD does not produce the buzz associated with THC, it has a minimal risk of abuse. A 2017 study from the Journal of Drug and Alcohol Dependence reviewed the results of a previous study, in which researchers administered different doses of oral CBD to regular marijuana smokers.
Studies conducted on animals and humans concluded that CBD is safer than THC and other cannabinoids. Researchers also found that CBD is well tolerated in humans, even in high doses up to 1,500 milligrams daily.
Addiction experts suggest that only 9% of marijuana users will become physically dependent on THC. The remaining 91% merely develop negative habits toward the substance that could later lead to abuse.
Since THC can be habit-forming, it’s important to know the difference between the two sources of CBD extracts: hemp and marijuana.
Hemp-Derived CBD vs Marijuana-Derived CBD
Cannabis sativa L. is both the parent and a source of CBD. These plants have different chemical profiles and ratios of THC to CBD despite sharing the same parent.
Despite its natural THC content, marijuana usually contains high amounts of the psychoactive chemical. Therefore, CBD oil derived from it will contain enough THC to give users a high.
Hemp plants usually contain 0.3% THC or less, but CBD oil from hemp will not create any intoxicating effects due to its low THC content. Hemp plants contain more CBD than THC.
In addition to being non-addictive, CBD derived from hemp plants is also federally legal, making it available over the internet and at major pharmacies, dispensaries, vape shops, and smoke shops.
At Royal CBD, we only make hemp-based extracts that are tested and certified by an independent laboratory to ensure they contain less than 0.3% THC and are compliant with the federal law.
CBD Could Help Fight Addiction, Studies Say
As part of its 2017 report on CBD, the World Health Organization discussed its safety and avoidance of abuse.
This article mentions that CBD can help eliminate addiction and withdrawal symptoms as well.
A study published in 2013 noted an effective decrease in symptoms of a 19-year-old woman with cannabis withdrawal syndrome after using CBD for 10 days.
another study published in Neuropsychopharmacology examined the effect of CBD-to-THC ratios on amplifying the effects of psychoactive compounds in subjects who took high-CBD strains compared with high-THC smokers.
as well as lower self-rated dependence on cannabis. The scientists concluded that CBD could be used in the treatment of cannabis dependence and other addictive disorders.
CBD could also help curb addiction to other substances, such as nicotine or opioids. According to a 2013 study published in Addictive Behaviors, a treatment of CBD over a week-long period reduced the number of cigarettes smoked by 40% in addicted subjects, while the placebo group didn’t show any significant difference.
There are also studies that prove consuming CBD could decrease the use of other addictive substances. In a 2018 study published in Neuropsychopharmacology, researchers administered CBD gel to lab rats that displayed addiction-like behavior toward alcohol or cocaine after voluntary use.
The research team found out that CBD was effective in reducing drug use in the rodents, and also curbed the side effects of addiction, such as anxiety and impulsivity.
An American Journal of Psychiatry study published in 2019 found that CBD may help people with cravings due to heroin addiction. Researchers examined 42 adults who had used heroin for an average of 13 years. Participants were divided into three groups.
Two groups received different doses of CBD. The third received a placebo:
- 800 mg CBD
- 400 mg CBD
When compared to the placebo group, those taking CBD significantly reduced anxiety and cravings during heroin addiction withdrawals.
What Are the Side Effects of CBD Oil? Can You Overdose on CBD?
You should avoid taking too much CBD oil at one time. It has a well-established safety profile.
CBD can have the following adverse effects:
- Dry mouth
- Lower blood pressure
- Changes in appetite
Being that CBD does not affect the part of the brain stem that controls breathing, it is impossible to overdose on it.
There’s also one important subject we feel obliged to cover.
CBD & Drug Interactions: Talk to Your Doctor
CBD uses a system called Cytochrome p450 to metabolize the majority of active pharmaceutical compounds. Inhibiting Cytochrome p450 in the liver, CBD prevents pharmaceutical compounds from being processed in the liver.
The mechanism involves the same effects that eating grapefruit along with your medication can have on their metabolism.
These interactions may result in a number of treatment-increasing side effects not actually caused by CBD. They may also decrease the efficacy of your treatment. Therefore, we recommend that you talk to your doctor if you are using pharmaceutical drugs and are afraid they may interact with CBD.
Read our guide on CBD-drug interactions for a full list of substances that are metabolized by Cytochrome 450.
CBD and Addiction: Bottom Line
A brain disease, addiction manifests itself through intense cravings for a particular substance despite harmful and detrimental consequences. Those who suffer from addiction problems show a number of symptoms, including poor cognition, impaired body functions, as well as behaviors that may compromise daily life.
Initial research suggests there is no link between CBD and changes in perception, judgment, or cognition. Without an euphoric feeling, the brain might not associate CBD with the reward centers. In addition, CBD has no withdrawal symptoms and can’t cause lethal overdoses.
Recent studies have concluded that CBD may be effective in curbing addiction to several substances, including alcohol, nicotine, opioids, and heroin. CBD may not only assist with the physiological effects of addiction, but it may also help individuals break bad habits related to various substances and activities.
All in all, it looks like CBD can be a useful tool against addiction in more than one area.